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Premature Ovarian Failure

About Premature Ovarian Failure

Premature Ovarian Failure (POF), also to as referred as premature ovarian insufficiency, is a condition in which the patient loses her ovarian function before the age of 40. There are many reasons for POF; however, the causes of many cases are still not confirmed. They may cause a decrease in the storage of follicle pools or a malfunction of follicles.

Treatment for Premature Ovarian Failure in ReLife

Hormone replacement will be initiated when a patient is diagnosed with POF due to the estrogen deficiency. Medication like Calcium and vitamin D supplements will also be applied. For patients developing the complication of fertility problems, addressing infertility is also included in the treatment plan. Nowadays, as new medical techniques like gene therapy and stem cell therapy are applied more frequently, the treatment of POF has a prosperous future due to the new innovative techniques.

Cell-based Gene Therapy

labUtilizing the molecular biology method, cell-based gene therapy is an innovative treatment method that implants the hepatocyte growth factor – HGF via autologous cells into the patient’s body. By targeting the damaged ovary, it continuously and stably repairs the patient’s ovary, so as to eliminate the inner factors that cause POF and achieve the best treatment result.

Adipose tissue is an active endocrine and paracrine organ, which secretes various cytokines and biological factors. The regular secretion of adipose tissue regulates and controls the balance of energy in body, and also plays a role in many procedures, such as anti-inflammation. Adipose tissue is full of adipose stem cells, which have the ability to be easily cultivated in vitro and multiple differentiation capacity. It can effectively participate in the regenerative and repair procedures of the damaged ovary.

By taking advantage of adipose stem cell tropism, HGF will be carried into the damaged ovarian region by adipose stem cells, enabling HGF to continuously and stably affect and improve the blood circulation, as well as improve the survival rate and efficiency of adipose stem cells, which makes the treatment effect much better than a single application of stem cell therapy. It plays a key role in overcoming reproductive disorders, repairing the impaired ovarian function, and promoting the balance of endocrine system.

Traditional Chinese Medicine

tcmTraditional Chinese Medicine is a green, safe and effective treatment method. Via acupuncture, traditional Chinese medicine, moxibustion and natural therapy, TCM can activate the positive Qi in the human body, promote the gonad axis to work normally, recover the ovarian function, improve the endocrine function as well as the general internal environment of body, and recover the functions of both the Chong channel and Ren channel. By adjusting the hypothalamus-pituitary-gonad (HPG) axis, it can recover the ovarian function, thereby achieving the balance between Yin and Yang, Qi and Blood, as well as the organs, which further benefit the recovery of the gonad axis function and the correction of POF.

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